Function: The ExpoCube is a novel Air Liquid Interface (ALI)/Transwell in vitro exposure system which permits highly reliable and effective deposition of aerosols onto cells and tissues.
Features: The ExpoCube’s patented use of thermophoresis increases the deposition efficiency of small particles without imparting unnatural electrostatic charges onto the aerosols.
The use of Transwells® permeable supports allows cells to uptake and secrete molecules separately on both their basal and apical surfaces, thereby carrying out metabolic activities in a more natural fashion.
The ExpoCube replicates human physiology more closely than traditional cellular exposure systems by preventing the exposure of the culture medium (i.e., the blood side) to the gas phase, thereby creating a more natural or “lung-like” exposure profile.